Pagan natural law theory is non-historical.  Human nature cannot change, and its condition has not changed.  We are what we are, and we are as we are, forever and ever.

Christian natural law theory is historical.  In itself human nature cannot change, but its condition can change, and it has.  We were created; we have lost our original integrity; the cure has been offered.

In the early modern era the playing field was altered.  Some tried to use natural law to deny, ignore, or marginalize salvation history.  Others tried to make profane history do the work of natural law, and the state do the work of God.

The first modern gambit is dead.  Variations on the second are still playing out.